Root element of the Molecular Interaction Format Describes one or more interactions as a self-contained unit. Multiple entries from different files can be concatenated into a single entrySet. Desciption of the source of the entry, usually an organisation Name(s) of the data source, for example the organisation name. Bibliographic reference for the data source. Example: A paper which describes all interactions of the entry. Cross reference for the data source. Example: Entry in a database of databases. Further description of the source. Data availability statements, for example copyrights Describes data availability, e.g. through a copyright statement. If no availability is given, the data is assumed to be freely available. All experiments in which the interactions of this entry have been determined Describes one set of experimental parameters, usually associated with a single publication. List of all interactors occurring in the entry Will be extended in future levels to include other interactor types e.g. small molecules. A protein object participating in an interaction. List of interactions Will be extended in future levels to include other interaction types e.g. biochemical reactions. A set of molecules interacting. Semi-structured additional description of the data contained in the entry. Refers to a unique object in an external database. A short alphanumeric label identifying an object. Not necessarily unique. Full, descriptive object name. Describes the biological source of an object, in simple form only the NCBI taxid. The names of the organism. The short label should be a common name if it exists. The full name should be the full name of the species (i.e. genus species). Description of the cell type. Currently no species-independent controlled vocabulary for cell types is available, therefore the choice of reference database(s) is open to the data provider. The subcellular compartement of the object. It is strongly recommended to refer to the Gene Ontology cellular component in this element. Description of the source tissue. Currently no species-independent controlled vocabulary for tissues is available, therefore the choice of reference database(s) is open to the data provider. A feature, e.g. domain, on a sequence. Reference to an external feature description, for example InterPro entry. Description and classification of the feature Location of the feature on the sequence of the interactor Experimental method used to identify the feature. Crossreference to an external database. Primary reference to an external database. Further external objects describing the object. A specified position a a sequence. A interval on a sequence. A location can be either a position, site or have a start and end, only start, only end or is an empty element if the position is unknown. Describes one set of experimental parameters. Publication describing the experiment. Refers to external database description of the experiment. The host organism in which the experiment has been performed. Experimental method to determine the interaction. External controlled vocabulary. Experimental method to determine the interactors involved in the interaction. External controlled vocabulary. Experimental method to determine the features of interactors. External controlled vocabulary. Confidence in this experiment. Usually a statistical measure. Semi-structured additional description of the experiment. Refers to an object within the same file by its id. A list of additional attributes. Open tag-value list to allow the inclusion of additional data. Bibliographic reference. Bibliographic reference in external database, usually PubMed. Alternative description of bibliographic reference if no external database entry is available. Names for an object. Reference to an external controlled vocabulary. Name of the controlled vocabulary term. Source of the controlled vocabulary term. E.g. the name of the CV and the term ID. Allows to reference an external controlled vocabulary, or to directly include a value if no suitable external definition is available. This contains the controlled vocabulary terms, as a short and optionally as a long form. Refers to the term of the controlled vocabulary in an external database. If no suitable external controlled vocabulary is available, this attributeList can be used to describe the term. Example: Attribute name: Mouse atlas tissue name; attribute value: spinal cord, day 30. Describes a protein interactor. Protein name(s). The short label is typically a short name that could appear as a label on a diagram. An interactor should have an xref whenever possible. If the interactor is not available in external databases, it must be characterised within this proteinInteractor object e.g. by its sequence. The normal source organism of the interactor. If a human protein has been expressed in yeast, this attribute would describe human. Amino acid sequence in uppercase A text describing the availability of data, e.g. a copyright statement. A molecular interaction. Name(s) of the interaction. Either refer to an already defined availability statement in this entry or insert description. References an availability statement already present in this entry. Describes the availability of the interaction data. If no availability is given, the data is assumed to be freely available. List of experiments in which this interaction has been determined. Either refer to an already defined experiment in this entry or insert description. References an experiment already present in this entry. An experiment in which this interaction has been determined. A list of molecules participating in this interaction. Will be extended in future levels to include other types of participant molecules. An interaction has two or more participants, thereby covering binary and n-ary interactions. External controlled vocabulary characterising the interaction type, for example "aggregation". Confidence in this interaction. Usually a statistical measure. Interaction database ID Semi-structured additional description of the data contained in the entry. A protein participating in an interaction. Either refer to an already defined protein interactor in this entry or insert description. References an interactor described in the interactorList of the entry Fully describes an interactor Sequence features relevant for the interaction, for example binding domains Confidence in participant detection. The role of the participant in the interaction, e.g. "bait". Choose an enumerated value. True if the protein has been tagged in the experiment. True if the protein has been overexpressed in the experiment.